The world number one defeated Dave Chisnall 11-6 in Sunday’s final, which he had reached by edging a thriller against Phil Taylor.
The Dutch ace had stormed to victories against Stephen Bunting and Michael Smith to set up a semi-final encounter with 16-time World Champion Taylor, where he survived a scare but turned a 9-6 deficit into a 11-10 victory before going on to see off Chisnall in the decider.
“I’m really happy to win this trophy,” said van Gerwen, who averaged 104 for the tournament. “I really had to work for this and it was a hard day.
“I had a bit of luck but you can’t ask for anything more than to be holding the trophy at the end. Phil missed seven match darts, which he normally never does, and when someone gives you a chance like that you have to take it.
“At 5-0 in the final I knew the game was over. I had a couple of good finishes afterwards, held my own throw and it was enough to win the game.
“It was a tough day and I feel fantastic. It means a lot to me and I’m really glad to win this Unibet Masters again.
“I started last year exactly the same and we start the Premier League this Thursday, so that’s my aim now. I’ll enjoy this win and get myself ready to play James Wade in Leeds.”